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Dr. Will Bulsiewicz explores the critical connection between gut health, the microbiome, and chronic inflammation, offering practical strategies to optimize health through diet, lifestyle, and emotional well-being.
A comprehensive exploration of addiction across substances and behaviors, focusing on the science, psychology, and treatment of addictive disorders, with insights from a leading expert on how to understand, prevent, and overcome addiction.
In this comprehensive AMA episode, Peter Attia provides an in-depth guide to cardiorespiratory fitness, explaining how zone 2 and VO2 max training can improve healthspan, lifespan, and long-term physical independence across different fitness levels and age groups.
Dr. Peter Attia shares insights on longevity, emphasizing the importance of muscle mass, cardiovascular fitness, emotional health, and strategic supplementation as key factors in living longer and better.
Professor David Nutt reveals the toxic nature of alcohol, explaining its harmful effects on health while also acknowledging its deep social benefits, and offers practical advice for mindful drinking and potential reduction.
Dr. Benjamin Bikman reveals how controlling insulin through a low-carb, ketogenic diet can help people lose weight, improve metabolic health, and reduce cravings by focusing on fat and protein intake while minimizing carbohydrates.
Dr. Dominic D'Agostino discusses the benefits of ketosis for mood, cognition, and potential long-term brain protection, sharing insights on metabolic health, exogenous ketones, and practical strategies for implementing a ketogenic diet.
A deep dive into the remarkable GLP-1 drugs that seem to help with weight loss, diabetes, addiction, neurological conditions, and more, exploring their mysterious mechanisms of moderation and potential future developments.
In this episode, Dr. Andrew Huberman shares insights on cortisol, sleep, health optimization, habit formation, and the importance of understanding the principles behind scientific practices, while also discussing his own spiritual journey and the value of giving over control to a higher power.
A comprehensive exploration of women's health across life stages, focusing on the critical role of exercise, nutrition, and hormones in building bone density, maintaining muscle mass, optimizing performance, and supporting metabolic health from childhood through menopause.
Dr. Rhonda Patrick discusses four key micronutrients—sulforaphane, omega-3s, vitamin D, and magnesium—and explores how deliberate cold and heat exposure can support cellular health, metabolism, and longevity through stress response pathways.
Dr. Betsy Grunch provides a comprehensive guide to taking control of your health through simple, sustainable lifestyle changes that focus on spine health, proper movement, nutrition, and understanding how small daily habits can significantly impact your long-term physical well-being.
Dr. Caroline Leaf reveals how depression and anxiety are not diseases but helpful messengers, and shares her neurocycle method for rewiring the mind, managing trauma, and achieving mental peace through deliberate, scientific mind management.
Two world-leading nutrition scientists, Tim Spector and Sarah Berry, reveal ZOE's eight science-backed principles for eating better in 2026, focusing on mindful eating, plant diversity, food quality, and gut health to help people feel more energetic and improve their overall well-being.
A comprehensive guide to brain health, exploring scientifically-backed strategies to optimize cognitive function, protect against neurological diseases, and maintain brain vitality through exercise, nutrition, mental practices, and understanding the impact of lifestyle choices.
Dr. Kyle Gillett discusses optimizing hormone health for men and women through lifestyle interventions like diet, exercise, stress management, sleep, sunlight exposure, and spiritual well-being, while exploring topics such as testosterone, PCOS, peptides, and the interconnectedness of physical, mental, and spiritual health.
Dr. Tara Swart reveals how chronic stress and constant digital stimulation are rewiring our brains, causing exhaustion and health issues, while offering science-backed strategies to improve mental resilience, focus, and overall well-being through simple micro-habits and understanding neuroplasticity.
A science-backed exploration of health tips for 2026, covering topics like sleep, nutrition, blood sugar management, arthritis, muscle preservation, and personalized lifestyle experiments.
A deep dive with biohacking pioneer Dave Asprey explores optimizing health, emotional regulation, and longevity through understanding mitochondrial function, nutrition, and personalized wellness practices.
Chris Hemsworth opens up about his childhood in the Australian outback, his acting journey, the profound impact of his father's Alzheimer's diagnosis, and the importance of family, connection, and staying present in a life often consumed by ambition and achievement.
A highlights episode showcasing the most impactful health and nutrition insights from 2025, featuring discussions on inflammation, fasting, brain health, and the rising popularity of matcha.
Jake Becraft describes how Strand Therapeutics is developing programmable mRNA technology to create targeted cancer treatments that activate the immune system to selectively attack tumor cells, potentially transforming cancer from a fatal disease to a manageable condition.
In a candid conversation with cardiologist Eric Topol, Adam Grant explores cutting-edge insights on longevity, debunking health myths, preventing major diseases, and the potential of AI in transforming medical care.
Dr. Daniel Amen reveals that 70% of chronic pain originates in the brain, explaining how negative thoughts, emotional suffering, and unprocessed trauma can create a "doom loop" of pain that impacts physical and mental health, and offers strategies to break this cycle through brain-focused healing.
An in-depth exploration of ketogenic diets, metabolic therapies, and exogenous ketones, examining their potential applications for weight loss, cognitive enhancement, cancer treatment, and neurological disorders through the lens of neuroscientist Dominic D'Agostino's groundbreaking research and personal experiences.
Anthony and TereZa Lolli share their transformative health journey from personal challenges to becoming biohacking pioneers, documenting their experiences through award-winning documentaries and inspiring millions to optimize their bodies, mindset, and life.
World-leading gut health expert Tim Spector reveals how fermented foods can dramatically transform well-being, explaining the powerful link between gut health and mental health, and offering practical steps to improve diet and mood through simple dietary shifts.
Dr. Michael Greger reveals the power of diet in reversing aging, discussing how simple lifestyle changes like eating legumes, nuts, reducing salt, and consuming whole grains can potentially add years to one's life and improve overall health.
Dr. Annette Bosworth reveals how a ketogenic diet can potentially reverse insulin resistance, improve brain health, reduce inflammation, and help manage chronic diseases by teaching people how to effectively "take out the trash" in their body through strategic nutrition and lifestyle changes.
An interview with Lada Nuzhna, founder of General Control, exploring her journey in biotech, the challenges of developing aging therapies, and her mission to engineer epigenetic medicines that could potentially extend human lifespan.
A compilation episode featuring leading experts Dr. Alan Goldhamer, Dr. Valter Longo, and Dr. Michael Greger discussing the science of fasting, its potential health benefits, various fasting protocols, and strategies for improving metabolic health and longevity.
Two venture capitalists explore the brutal economics of biotech, revealing why the industry is struggling despite scientific advances, and how new modalities, AI, and a focus on invention could revive innovation in drug development.
Dr. Ellen Langer reveals how our thoughts directly influence our physical health, demonstrating through groundbreaking research that mindfulness, uncertainty, and reframing our perceptions can reverse aging, heal chronic conditions, and transform our understanding of wellness.
Dr. Jack Feldman discusses the intricate mechanics of breathing, its neural circuits, and profound impacts on mental and physical health, exploring how breath patterns can influence emotional states, reduce anxiety, and enhance cognitive performance.
Tim Ferriss shares his personal journey of overcoming childhood sexual abuse and depression, revealing science-backed mental health tools like vagus nerve stimulation, accelerated TMS, metabolic psychiatry, and psychedelic therapy.
Ben Patrick shares how he transformed from a chronically injured athlete to a fitness innovator by challenging conventional exercise wisdom, developing a minimalist training approach focused on joint health, range of motion, and strength through methods like backward sled pulls and full-range squats.
In this episode, Preston Pysh and Seb Bunney explore David Sinclair's book "Lifespan", discussing the information theory of aging, epigenetics, Yamanaka factors, and the potential for science to slow or reverse the aging process through cellular repair and regeneration.
Dr. Paul Taylor explores how choosing the challenging path of hardiness—through psychological resilience and physiological stress exposure—can lead to a more meaningful, healthier, and longer life in the modern world of comfort and convenience.
Dr. David Sinclair discusses the biological mechanisms of aging, highlighting how lifestyle choices like fasting, low glucose levels, and specific supplements can activate longevity pathways and potentially slow or reverse aspects of the aging process.
Celine Halioua discusses her company Loyal's groundbreaking work developing a daily pill for dogs that could extend their lifespan by at least one year, with the first therapy potentially available in 2026 and the potential to pave the way for human longevity research.
Joel Kocher, CEO of Humann, shares his journey of discovering nitric oxide, building a $200M company focused on cardiovascular health, and revealing the importance of adaptability, talent acquisition, and doing things right over doing them quickly.
Andrew Huberman explains the lymphatic system's crucial role in overall health and appearance, providing science-based tools to support lymphatic drainage, reduce fluid retention, eliminate brain fog, and improve cardiac and brain health through techniques like movement, breathing, massage, and exercise.
A panel of leading women's health experts delve into the critical importance of exercise, nutrition, and lifestyle choices for women's health, focusing on muscle building, bone density, hormonal changes, and strategies for optimal well-being across different life stages.
A comprehensive overview of Peter Attia's approach to longevity, focusing on extending both lifespan and healthspan through strategic interventions in exercise, nutrition, sleep, pharmacology, and emotional health.
Discover how to build a scientifically-backed gratitude practice that leverages story-based narratives and receiving genuine thanks to activate neural circuits that reduce anxiety, boost motivation, lower inflammation, and enhance overall mental and physical well-being.
Mel Robbins sits down with Mayo Clinic physician and cancer survivor Dr. Dawn Mussallem to explore five cancer-fighting foods and lifestyle changes that can heal your body and prevent disease.
A comprehensive exploration of the auditory system, hearing loss prevention, and the critical links between hearing, brain health, emotional well-being, and cognitive function.
A deep dive into protein intake, exploring the historical demonization of macronutrients, challenging the Recommended Dietary Allowance (RDA), discussing potential benefits of higher protein consumption, and examining the nuanced perspectives on processed foods.
Robert Lustig reveals how sugar and ultra-processed foods can rewire your brain, impact mental health, and contribute to diseases like Alzheimer's, while offering practical strategies to reclaim health and break free from food addiction.
In this episode, renowned sugar expert Dr. Robert Lustig explains how sugar and ultra-processed foods can rewire your brain, contribute to addiction, and potentially lead to serious health issues like dementia and cancer.
Ben Greenfield shares insights on biohacking, parenting, and life priorities, emphasizing the importance of prioritizing spiritual growth, family connections, health, and serving others before business success.
Ben Greenfield shares insights on designing a life and home optimized for longevity, blending ancestral wisdom with modern science, and emphasizing family, faith, and daily movement over extreme biohacking.
In this episode, renowned cardiologist Dr. Pradip Jamnadas discusses the critical role of insulin, diet, lifestyle, and inflammation in heart health, emphasizing the importance of fasting, gut health, and understanding the body's metabolic processes to prevent cardiovascular disease.
A roundtable discussion exploring strength training, resistance exercise, nutrition, and athletic development, featuring insights from experts Gabrielle Lyon, Mike Boyle, and Jeff Cavaliere on the critical importance of muscle health, injury prevention, and lifelong fitness across different age groups.
A deep dive into optimizing exercise, nutrition, and recovery strategies with insights on resistance training, hormonal responses, metabolic efficiency, and the importance of individualized, science-driven approaches to physical performance.
Doctor Eric Topol discusses the alarming health risks posed by microplastics, forever chemicals, and environmental toxins, revealing how these pervasive substances are impacting human health and potentially contributing to rising rates of cancer, infertility, and other diseases.
Dr. Michael Snyder shares insights into personalized health, exploring how individual variations in metabolism, genetics, and lifestyle impact glucose regulation, organ aging, and overall well-being. Through innovative research and technology, he demonstrates the importance of comprehensive, data-driven approaches to understanding and improving human health, emphasizing that one-size-fits-all medical advice is insufficient.
In this episode, Dr. Andrew Kutnik discusses the profound impact of diet, particularly the ketogenic diet, on metabolic health, highlighting how nutrition can be as powerful as medicine in managing chronic diseases like diabetes. Through his personal journey and extensive research, he explores how controlling glucose levels, reducing carbohydrate intake, and understanding metabolic responses can dramatically improve overall health, cognitive function, and performance.
Bryan Johnson shares his mission to improve human survival through a radical longevity protocol involving precise nutrition, extensive supplementation, and comprehensive health tracking. He discusses his transformative journey from experiencing poverty in Ecuador to developing a detailed personal health system aimed at maximizing biological potential and slowing aging.
Dr. Dominic D'Agostino discusses the potential benefits of ketones, ketogenic diets, and exogenous ketones for various conditions including neurodegenerative diseases, cancer, and mental health, drawing from his extensive research in metabolic therapies. The episode explores topics ranging from the metabolic effects of ketones to practical strategies for implementing ketogenic diets and supplementation, with a focus on personalized approaches to health optimization.
Oliver Anwar, an executive health coach, shares insights on optimizing physical health for high-performance business leaders through comprehensive blood work, strategic supplementation, and tailored fitness approaches. He emphasizes that improving body composition, managing sleep, and maintaining peak physical condition can directly impact business success and personal well-being.
Here's a two-sentence description for the episode: Dan Buettner, a National Geographic Explorer and bestselling author, reveals the secrets of longevity from Blue Zones around the world, explaining how environment, diet, and lifestyle choices can significantly extend life expectancy. Through fascinating stories and scientific research, he shares practical insights on how to create a healthier, more purposeful life by adopting habits from the world's longest-living populations.
Here's a two-sentence description for the episode: Dr. Alan Goldhamer, a pioneering physician, discusses the profound health benefits of water fasting, revealing how it can help reset the gut microbiome, reduce visceral fat, and potentially reverse chronic conditions like high blood pressure and certain cancers. Through medically supervised fasting protocols ranging from 5 to 40 days, he explains how the body can heal itself by mobilizing fat, reducing inflammation, and creating significant physiological and psychological transformations.
Here's a two-sentence description for the episode: In this episode of The Diary of a CEO, fat burning expert Alan Arragon breaks down critical insights about nutrition, protein intake, weight loss, and fitness, covering topics ranging from diet strategies and muscle gain to overcoming plateaus and maintaining motivation. The conversation also delves into Alan's personal journey of overcoming alcohol addiction and transforming his health, offering listeners practical advice and scientific perspectives on achieving their fitness goals.